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1

Hayes' Handbook of Pesticide Toxicology || Dose and Time Determining, and Other Factors Influencing, Toxicity

Rozman, Karl K.

Year:

2010

Language:

english

File:

PDF, 7.76 MB

english, 2010

2

Hazard Evaluation in Risk Assessment: Whatever Happened to Sound Scientific Judgment and Weight of Evidence?

Doull, John, Rozman, Karl K., Lowe, Michael C.

Journal:

Drug Metabolism Reviews

Year:

1996

Language:

english

File:

PDF, 826 KB

english, 1996

3

NTP-CERHR Expert Panel Report on the reproductive and developmental toxicity of soy formula

Karl K. Rozman, Jatinder Bhatia, Antonia M. Calafat, Christina Chambers, Martine Culty, Ruth A. Etzel, Jodi A. Flaws, Deborah K. Hansen, Patricia B. Hoyer, Elizabeth H. Jeffery, James S. Kesner, Sue M

Journal:

Birth Defects Research Part B: Developmental and Reproductive Toxicology

Year:

2006

Language:

english

File:

PDF, 1.04 MB

english, 2006

4

NTP-CERHR expert panel report on the reproductive and developmental toxicity of genistein

Karl K. Rozman, Jatinder Bhatia, Antonia M. Calafat, Christina Chambers, Martine Culty, Ruth A. Etzel, Jodi A. Flaws, Deborah K. Hansen, Patricia B. Hoyer, Elizabeth H. Jeffery, James S. Kesner, Sue M

Journal:

Birth Defects Research Part B: Developmental and Reproductive Toxicology

Year:

2006

Language:

english

File:

PDF, 1.29 MB

english, 2006

5

Dose-response and time course of hypothyroxinemia and hypoinsulinemia and characterization of insulin hypersensitivity in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-treated rats

Joel R. Gorski, Karl Rozman

Journal:

Year:

1987

Language:

english

File:

PDF, 554 KB

english, 1987

6

Elevated plasma corticosterone levels and histopathology of the adrenals and thymuses in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated rats

Joel R. Gorski, Giacomo Muzi, Lutz W. Weber, David W. Pereira, Michael J. Iatropoulos, Karl Rozman

Journal:

Year:

1988

Language:

english

File:

PDF, 4.58 MB

english, 1988

7

Reduced activities of key enzymes of gluconeogenesis as possible cause of acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in rats

Lutz W.D. Weber, Margitta Lebofsky, Bernhard U. Stahl, Joel R. Gorski, Giacomo Muzi, Karl Rozman

Journal:

Year:

1991

Language:

english

File:

PDF, 843 KB

english, 1991

8

Reduction of hepatic phosphoenolpyruvate carboxykinase (PEPCK) activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is due to decreased mRNA levels

Bernhard U. Stahl, David G. Beer, Lutz W.D. Weber, Karl Rozman

Journal:

Year:

1993

Language:

english

File:

PDF, 819 KB

english, 1993

9

Subchronic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and their reversibility in male Sprague-Dawley rats

Xuelin Li A, Karl K. Rozman

Journal:

Year:

1995

Language:

english

File:

PDF, 691 KB

english, 1995

10

Reduced activity of tryptophan 2,3-dioxygenase in the liver of rats treated with chlorinated dibenzo-p-dioxins (CDDs): Dose-responses and structure-activity relationship

Lutz W.D. Weber, Cindy D. Palmer, Karl Rozman

Journal:

Year:

1994

Language:

english

File:

PDF, 414 KB

english, 1994

11

Validation of Haber's Rule (dose × time = constant) in rats and mice for monochloroacetic acid and 2,3,7,8-tetrachlorodibenzo-p-dioxin under conditions of kinetic steady state

Shakil A. Saghir, Margitta Lebofsky, David M. Pinson, Karl K. Rozman

Journal:

Year:

2005

Language:

english

File:

PDF, 229 KB

english, 2005

12

Gonadotropin-releasing hormone (GnRH) partially reverses the inhibitory effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on ovulation in the immature gonadotropin-treated rat

Xin Gao, Brian K Petroff, Karl K Rozman, Paul F Terranova

Journal:

Year:

2000

Language:

english

File:

PDF, 154 KB

english, 2000

13

Occupational exposure limits for 30 organophosphate pesticides based on inhibition of red blood cell acetylcholinesterase

Jan E Storm, Karl K Rozman, John Doull

Journal:

Year:

2000

Language:

english

File:

PDF, 321 KB

english, 2000

14

The role of time in toxicology or Haber’s c×t product

Journal:

Year:

2000

Language:

english

File:

PDF, 123 KB

english, 2000

15

A review of mechanisms controlling ovulation with implications for the anovulatory effects of polychlorinated dibenzo-p-dioxins in rodents

Brian K. Petroff, Katherine F. Roby, Xin Gao, Deok-Soo Son, Shalmica Williams, Donald Johnson, Karl K. Rozman, Paul F. Terranova

Journal:

Year:

2001

Language:

english

File:

PDF, 358 KB

english, 2001

16

Paracelsus, Haber and Arndt

Karl K. Rozman, John Doull

Journal:

Year:

2001

Language:

english

File:

PDF, 82 KB

english, 2001

17

Estradiol enhances and estriol inhibits the expression of CYP1A1 induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in a mouse ovarian cancer cell line

Deok-Soo Son, Katherine F Roby, Karl K Rozman, Paul F Terranova

Journal:

Year:

2002

Language:

english

File:

PDF, 568 KB

english, 2002

18

Decreased liver type I 5′-deiodinase and increased brown adipose tissue type II 5′-deiodinase activity in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-treated Long-Evans rats

Atso Raasmaja, Matti Viluksela, Karl K. Rozman

Journal:

Year:

1996

Language:

english

File:

PDF, 564 KB

english, 1996

19

Cytokines (IL-1β and TNFα) in relation to biochemical and immunological effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in rats

Fang Fan, Binfang Yan, Gary Wood, Matti Viluksela, Karl K. Rozman

Journal:

Year:

1997

Language:

english

File:

PDF, 696 KB

english, 1997

20

Dose and time as variables of toxicity

Karl K. Rozman, John Doull

Journal:

Year:

2000

Language:

english

File:

PDF, 120 KB

english, 2000

21

Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in cold-adapted rats

Karl Rozman, Helmut Greim

Journal:

Archives of Toxicology

Year:

1986

Language:

english

File:

PDF, 409 KB

english, 1986

22

Composition of diet modifies toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in cold-adapted rats

Giacomo Muzi, Joel R. Gorski, Karl Rozman

Journal:

Archives of Toxicology

Year:

1987

Language:

english

File:

PDF, 601 KB

english, 1987

23

Tissue-specific alterations of de novo fatty acid synthesis in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-treated rats

Joel R. Gorski, Lutz W. D. Weber, Karl Rozman

Journal:

Archives of Toxicology

Year:

1988

Language:

english

File:

PDF, 687 KB

english, 1988

24

Comparative toxicity of four chlorinated dibenzo-p-dioxins (CDDs) and their mixture

Lutz W. D. Weber, Margitta Lebofsky, Bernhard U. Stahl, Antonius Kettrup, Karl Rozman

Journal:

Archives of Toxicology

Year:

1992

Language:

english

File:

PDF, 520 KB

english, 1992

25

Comparative toxicity of four chlorinated dibenzo-p-dioxins (CDDs) and their mixture

Bernhard U. Stahl, Antonius Kettrup, Karl Rozman

Journal:

Archives of Toxicology

Year:

1992

Language:

english

File:

PDF, 658 KB

english, 1992

26

Comparative toxicity of four chlorinated dibenzo-p-dioxins (CDDs) and their mixture

Lutz W. D. Weber, Margitta Lebofsky, Bernhard U. Stahl, Antonius Kettrup, Karl Rozman

Journal:

Archives of Toxicology

Year:

1992

Language:

english

File:

PDF, 618 KB

english, 1992

27

Reduced gluconeogenesis in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-treated rats

Joel R. Gorski, Lutz W. D. Weber, Karl Rozman

Journal:

Archives of Toxicology

Year:

1990

Language:

english

File:

PDF, 612 KB

english, 1990

28

Key enzymes of gluconeogenesis are dose-dependently reduced in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-treated rats

Lutz W. D. Weber, Margitta Lebofsky, Helmut Greim, Karl Rozman

Journal:

Archives of Toxicology

Year:

1991

Language:

english

File:

PDF, 554 KB

english, 1991

29

Penetration, distribution and kinetics of 2,3,7,8-tetrachlorodibenzo-p-dioxin in human skin in vitro

Lutz W. D. Weber, Achim Zesch, Karl Rozman

Journal:

Archives of Toxicology

Year:

1991

Language:

english

File:

PDF, 822 KB

english, 1991

30

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces plasminogen activator inhibitor-1 through an aryl hydrocarbon receptor-mediated pathway in mouse hepatoma cell lines

Deok-Soo Son, Karl K. Rozman

Journal:

Archives of Toxicology

Year:

2002

Language:

english

File:

PDF, 287 KB

english, 2002

31

Relationship between acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and disturbance of intermediary metabolism in the Long-Evans rat

Fang Fan, Karl K. Rozman

Journal:

Archives of Toxicology

Year:

1994

Language:

english

File:

PDF, 624 KB

english, 1994

32

Comparative toxicity of four chlorinated dibenzo-p-dioxins (CDDs) and their mixture

Karl K. Rozman, Bernhard U. Stahl, Laszlo Kerecsen, Antonius Kettrup

Journal:

Archives of Toxicology

Year:

1995

Language:

english

File:

PDF, 420 KB

english, 1995

33

Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on tryptophan and glucose homeostasis in the most TCDD-susceptible and the most TCDD-resistant species, guinea pigs and hamsters

Mikko Unkila, Marjatta Ruotsalainen, Raimo Pohjanvirta, Matti Viluksela, Ewen MacDonald, Jouni T. Tuomisto, Karl Rozman, Jouko Tuomisto

Journal:

Archives of Toxicology

Year:

1995

Language:

english

File:

PDF, 676 KB

english, 1995

34

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on liver phosphoenolpyruvate carboxykinase (PEPCK) activity, glucose homeostasis and plasma amino acid concentrations in the most TCDD-susceptible and the most TCDD-resistant rat strains

Matti Viluksela, Mikko Unkila, Raimo Pohjanvirta, Jouni T. Tuomisto, Bernhard U. Stahl, Karl K. Rozman, Jouko Tuomisto

Journal:

Archives of Toxicology

Year:

1999

Language:

english

File:

PDF, 234 KB

english, 1999

35

Hexadecane enhances non-biliary, intestinal excretion of stored hexachlorobenzene by rats

Karl Rozman, Tibor Rozman, Lothar Ballhorn, Helmut Greim

Journal:

Year:

1982

Language:

english

File:

PDF, 355 KB

english, 1982

36

Effect of thyroid hormones on liver microsomal enzyme induction in rats exposed to 2,3,7,8,-tetra-chlorodibenzo-p-dioxin

Karl Rozman, George A. Hazelton, Curtis D. Klaassen, Michael P. Arlotto, Andrew Parkinson

Journal:

Year:

1985

Language:

english

File:

PDF, 717 KB

english, 1985

37

Correlation between acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and total body fat content in mammals

Harald J. Geyer, Irene Scheuntert, Karl Rapp, Antonius Kettrup, Friedhelm Korte, Helmut Greim, Karl Rozman

Journal:

Year:

1990

Language:

english

File:

PDF, 485 KB

english, 1990

38

A review of the relationship between acute toxicity (LC50) of γ-hexachlorocyclohexane (γ-HCH, Lindane) and total lipid content of different fish species

Harald J. Geyer, Christian E. Steinberg, Irene Scheunert, Rainer Brüggemann, Werner Schütz, Antonius Kettrup, Karl Rozman

Journal:

Year:

1993

Language:

english

File:

PDF, 557 KB

english, 1993

39

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on humoral and cell-mediated immunity in Sprague-Dawley rats

Fang Fan, Daniel Wierda, Karl K. Rozman

Journal:

Year:

1996

Language:

english

File:

PDF, 717 KB

english, 1996

40

Incorporation of First-Order Uptake Rate Constants from Simple Mammillary Models into Blood-Flow Limited Physiological Pharmacokinetic Models via Extraction Efficiencies

William L. Roth, L. W. D. Weber, Karl K. Rozman

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 969 KB

1995

41

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Increases Release of Luteinizing Hormone and Follicle-Stimulating Hormone from the Pituitary of Immature Female Ratsin Vivoandin Vitro

Xuelin Li, Donald C. Johnson, Karl K. Rozman

Journal:

Toxicology and Applied Pharmacology

Year:

1997

Language:

english

File:

PDF, 127 KB

english, 1997

42

Subchronic/Chronic Toxicity of 1,2,3,4,6,7,8-Heptachlorodibenzo-p-dioxin (HpCDD) in Rats

Matti Viluksela, Bernhard U. Stahl, Linda S. Birnbaum, Karl-Werner Schramm, Antonius Kettrup, Karl K. Rozman

Journal:

Toxicology and Applied Pharmacology

Year:

1997

Language:

english

File:

PDF, 191 KB

english, 1997

43

Subchronic/Chronic Toxicity of 1,2,3,4,6,7,8-Heptachlorodibenzo-p-dioxin (HpCDD) in Rats

Matti Viluksela, Bernhard U. Stahl, Linda S. Birnbaum, Karl K. Rozman

Journal:

Toxicology and Applied Pharmacology

Year:

1997

Language:

english

File:

PDF, 201 KB

english, 1997

44

Subchronic/Chronic Toxicity of a Mixture of Four Chlorinated Dibenzo-p-dioxins in Rats

Matti Viluksela, Bernhard U. Stahl, Linda S. Birnbaum, Karl K. Rozman

Journal:

Toxicology and Applied Pharmacology

Year:

1998

Language:

english

File:

PDF, 151 KB

english, 1998

45

Toxic Equivalency Factors of Polychlorinated Dibenzo-p-dioxins in an Ovulation Model: Validation of the Toxic Equivalency Concept for One Aspect of Endocrine Disruption

Xin Gao, Deok-Soo Son, Paul F. Terranova, Karl K. Rozman

Journal:

Toxicology and Applied Pharmacology

Year:

1999

Language:

english

File:

PDF, 465 KB

english, 1999

46

Effects of Polychlorinated Dibenzofurans, Biphenyls, and Their Mixture with Dibenzo-p-dioxins on Ovulation in the Gonadotropin-Primed Immature Rat: Support for the Toxic Equivalency Concept

Xin Gao, Paul F. Terranova, Karl K. Rozman

Journal:

Toxicology and Applied Pharmacology

Year:

2000

Language:

english

File:

PDF, 298 KB

english, 2000

47

2,3,7,8-Tetrachlorodibenzo-p-dioxin Decreases Responsiveness of the Hypothalamus to Estradiol as a Feedback Inducer of Preovulatory Gonadotropin Secretion in the Immature Gonadotropin-Primed Rat

Xin Gao, Kaori Mizuyachi, Paul F. Terranova, Karl K. Rozman

Journal:

Toxicology and Applied Pharmacology

Year:

2001

Language:

english

File:

PDF, 617 KB

english, 2001

48

Endocrine Disruption by Indole-3-carbinol and Tamoxifen: Blockage of Ovulation

Xin Gao, Brian K. Petroff, Okunola Oluola, Gunda Georg, Paul F. Terranova, Karl K. Rozman

Journal:

Toxicology and Applied Pharmacology

Year:

2002

Language:

english

File:

PDF, 572 KB

english, 2002

49

Liquid paraffins in feed enhance fecal excretion of mirex and DDE from body stores of lactating goats and cows

Karl Rozman, Tibor Rozman, G. Stanley Smith

Journal:

Bulletin of Environmental Contamination and Toxicology

Year:

1984

Language:

english

File:

PDF, 475 KB

english, 1984

50

Stimulation of nonbiliary, intestinal excretion of hexachlorobenzene in rhesus monkeys by mineral oil

Karl Rozman, Tibor Rozman, Helmut Greim

Journal:

Toxicology and Applied Pharmacology

Year:

1983

Language:

english

File:

PDF, 590 KB

english, 1983